Baclofen, sold under the brand name Lioresal among others, is a medication used to treat spasticity. It serves as a central nervous system depressant and skeletal muscle relaxant. It is also used in topical creams to help with pain. Opsonin pharma product list pdf receptors, specifically the GABAB receptors.
Its beneficial effects in spasticity result from its actions in the brain and spinal cord. As of 2015 the cost for a typical course of treatment in the United States is less than 25 USD. Baclofen is primarily used for the treatment of spastic movement disorders, especially in instances of spinal cord injury, cerebral palsy, and multiple sclerosis. Its use in people with stroke or Parkinson’s disease is not recommended.
Baclofen is being studied for the treatment of alcoholism. While evidence is promising that it may help with alcohol withdrawal syndrome, as of 2017 it is not strong enough to recommend its use for this purpose.